Newcrom Columns
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
SIELC Technologies introduces a new type of mixed-mode separation media. By further improving on mixed-mode methodology, a new generation of separation media was developed. This new generation of columns offers a significant step in obtaining a universal platform for all types of small molecule separation. Previous generations of the mixed-mode media suffer from such limitations as restricted use of methanol in the mobile phase, poor peak shape, low efficiency for multi-charged molecules, high buffer concentration requirement and poor retention of non-charged molecules. All these limitations have been overcome with the Newcrom stationary phase.
The new surface chemistry is based on the idea of moving the charged embedded functional groups as far from silica gel surface as possible.
